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Discover › NCCIH Natural Product Early Phase Clinical Trial Award...

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

National Institutes of Health Grant

Open

Next step

Application exact time to be confirmed about 9 days

Show times in

Award

≤ US$1,050,000

Award ceiling US$1,050,000

Total pool (not per award): US$1,050,000 Estimated total program funding (Grants.gov)

Source

Last verified: 2026-11-04 (structured source)
Last checked automatically: 2026-11-04 12:51 UTC
First seen: 2026-11-04

Official page ↗

Guidelines ↗

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What it supports

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results,…

Application stages

StageDeadlineWhoSource wording
Application due (Grants.gov close date)
Application

exact time to be confirmed
All applicants closeDate 11/13/2026

Who can apply

Eligible applicant types (Grants.gov): For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Public housing authorities/Indian housing authorities; Private institutions of higher education; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Independent school districts; Native American tribal governments (Federally recognized); Small businesses; City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Institution country
Most Grants.gov opportunities require US-based applicants; check the listing's eligibility section.
Nationality
Not stated
Residence
Not stated
Where the work happens
Not stated
Funder country
United States (not an eligibility rule)
Career stage
Not stated
Applicant type
Institution

Key conditions

Nomination required
Not stated
Relocation / mobility required
Not stated
Partner required
Not stated
Matching funds required
No

Check against my profile

Explainable rules only — no probability scores. Missing information is shown as 'to check', never as 'not eligible'.

Edit my profile (stored only in this browser)

My private notes (this browser only)

These never replace the official deadline and are not sent to the server.

Evidence & update history

Source: Grants.gov (US federal) – official REST API (api, Health: degraded)

Change history

  • 2026-11-04 12:52 — *: ∅ → created (automatic)